iPSC Derived Cells
iPSC-Derived Hepatocytes (iHeps)
Allele’s iPSC-derived hepatocytes (iHeps) are mature, highly functional, and designed for extended culture performance. While other suppliers recommend maintaining iHeps for up to two weeks, our cultures remain healthy and active for two months or more, offering greater experimental flexibility and more biologically relevant long-term data.
These cells express key hepatic markers, demonstrate robust cytochrome P450 activity, and exhibit proper glycogen storage and albumin secretion over extended periods. Every lot is validated for viability, morphology, and metabolic function to ensure consistent, reproducible results.
Our ongoing studies show strong maintenance of hepatic phenotype and functionality in long-term culture. Additional data sets are being prepared to further illustrate gene expression stability, enzyme activity, and long-term metabolic consistency.
With their exceptional longevity and function, Allele iHeps are ideal for applications in toxicity testing, disease modeling, and drug metabolism studies — bridging the gap between short-term cultures and in vivo models.
